ePoster · Neuroscience
Gradual changes in TMS-induced motor excitability are associated with excitation-inhibition balance dynamics
Lisa Haxel, Paolo Belardinelli, Jakob H. Macke, Ulf Ziemann · FENS Forum 2024
Single-pulse transcranial magnetic stimulation (spTMS) applied to the primary motor cortex (M1) is widely used to assess corticospinal excitability through motor evoked potentials (MEPs). While trial-by-trial variability in MEP amplitude is thought to reflect dynamic shifts in cortical excitability, implications and neural underpinnings of gradual changes in MEP amplitude over the course of a spTMS session remain unexplored. We addressed this gap by investigating the relationship between slow MEP amplitude fluctuations and shifts in electroencephalography (EEG)-derived excitation/inhibition (E