Topic: SLCs

Solute carrier proteins (SLCs) are a vast superfamily of membrane proteins found on organelles and the plasma membrane of cells. Their role is to regulate the flux of a big variety of molecules across membranes and therefore modulate cellular homeostasis and function. In neurons, SLCs influence gene regulation, metabolic functions, and synaptic properties. Indeed, current research indicates that they play a pivotal role in several diseases.Previous published proteomic analyses show that several SLCs are frequently found in the membrane of extracellular vesicles (EVs) obtained from different bi