Topic: Sleep-associated hippocampal reactivations

Sleep-associated hippocampal reactivations are thougt to be central to the processing of memories and in particular to their consolidation. Nevertheless, it is unclear whether reactivated assemblies are static or whether they reorganize gradually over prolonged sleep. In this study, we tracked the neural activity of principal hippocampal cells in CA1 from the acquisition of a spatial memory, through an extended rest period (~20 hours) to its recall. We applied multiple decoding strategies to track the evolution of memory related activity over several hours of sleep.We observed that while durin