Topic: sleep slow oscillation

Brain rhythms of sleep influence sleep-associated memory consolidation. The modulation of sleep rhythms, such as the sleep slow oscillation (SO), can be used to investigate neurophysiological mechanisms of memory consolidation and the impact of sleep. Previously, closed-loop acoustic stimulation (CLAS) in humans during the SO Up-state successfully enhanced the slow oscillation rhythm and phase dependent spindle activity, although effects on memory retention have varied. Closely comparative studies in rodents that also monitor hippocampal activity are rare [1, 2]. Yet, a recent iEEG study [3] a