Topic: slow-wave sleep

Accumulating evidence from electrocorticogram (ECoG) recordings and imaging challenge traditional views of brain oscillations as spatially stationary periodic sources. Understanding the spatio-temporal dynamics of cortical activity requires novel measurement and analysis methodologies. We recorded broadband local field potential (LFP) across the whole neocortex in freely behaving rats using high-density flexible surface arrays using active transistors. 3D tracking and spatio-spectral analysis of recordings over long sessions enabled automatic and accurate brain and behavioral states segmentati

Slow brain rhythms, observed during slow-wave sleep or seizures, often coincide with oscillations in extracellular potassium levels. These rhythms have a lower frequency compared to a typical neuron’s tonic firing. Mechanisms organizing these rhythms are believed to rely on synaptic interactions within the network or intrinsic cellular voltage dynamics, likely a combination of both. This study focuses on single neurons that can produce slow rhythms, which in turn can organize slow rhythms in neural networks. Common theories attribute intrinsic slow bursting of neurons to ion channels with slow