Neurotrophins in adolescent brain rat are not altered by methamphetamine exposure during early postnatal period
Romana Šlamberová, Barbora Čechová, Lýdia Mihalčíková, Štěpán Šandera, Šimon Vaculín · FENS Forum 2024
Methamphetamine (MA) is a highly addictive psychostimulant abused worldwide that causes long-term behavioral changes that are linked to changes in the brain. The third trimester and adolescence are critical periods of development as the body undergoes dramatic changes and becomes more sensitive to the effects of the drug. This study aimed to investigate the effect of MA exposure during the first 12 postnatal days of laboratory rats, corresponding to the human third trimester, on hippocampal neurotrophin levels in adolescence. Exposure was performed either directly (daily subcutaneous injection
ePoster · Neuroscience