Unveiling astrocyte complexity: Calcium signaling dynamics and morphological heterogeneity
Kerstin Lenk, Aapo Tervonen · FENS Forum 2024
Astrocytes, a crucial glial cell type in the brain, play a vital role in maintaining ion and energy homeostasis while actively participating in neuronal information processing and memory formation. Calcium is considered the main readout signal of astrocytes. Several studies have shown a significant heterogeneity in morphology within brain regions like the hippocampus. To enhance our understanding of the morphology and function of cells, computational models can aid experiments. Oschmann et al. proposed a computational model integrating two glutamate pathways triggering calcium elevations: acti
ePoster · Neuroscience