Signatures of rapid synaptic learning in the hippocampus during novel experiences
James Priestley,John Bowler,Sebi Rolotti,Stefano Fusi,Attila Losonczy · COSYNE 2022
Neurons in the hippocampus exhibit striking selectivity for specific combinations of sensory features, forming representations which are thought to subserve episodic memory. Even during a completely novel experience, ensembles of hippocampal ``place cells'' are rapidly configured such that the population sparsely encodes visited locations, stabilizing within minutes of the first exposure to a new environment. What cellular mechanisms enable this fast encoding of experience? Recent work has implicated a novel “behavioral-timescale” synaptic plasticity (BTSP) rule in hippocampal area CA1 which c
ePoster · Neuroscience