Topic: somatomotor network

Pain is constructed in the brain by integrating multimodal information, ranging from noxious inputs to expectations. Previous studies have identified brain systems that mediate the effects of different components of pain, but the computational mechanisms of their integration have been understudied. Here we examined whether the neural trajectories of different component subspaces would reveal the computational principles of information integration. To this end, we conducted a cue-induced pain expectation experiment with functional Magnetic Resonance Imaging in humans (N = 56) to examine the com