Asymmetric metabolism controls the developing axon complexity in post-mitotic neurons
Fumi Suomi, Anna Rappe, Frédéric Clotman, Thomas McWilliams · FENS Forum 2024
Aims: Metabolic profile impacts on tissue development including neurons in brain, yet the full repertoire of metabolic signals that shape developing neuronal architecture remain mysterious. Our aim is to clarify the metabolic crosstalk that coordinates the early acquisition of the neurite complexity in developing neurons. Methods: To investigate the factors involved in metabolic switch, we used transcriptomics analysis on the sensory neurons cultured in different metabolic demand. IPA analysis was used to interpret the transcriptomics data. We applied MEME-ChIP method on comprehensive motif an
ePoster · Neuroscience