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Topic: spatially ordered spiking neuron networks

ePoster
1 ePoster

In Neuroscience

ePoster · Neuroscience

State modulation in spatial networks with three interneuron subtypes

Chengcheng Huang, Madeline Edwards, Jonathan Rubin · COSYNE 2025

Neuronal responses to sensory stimuli are strongly modulated by an animal’s brain state. Three distinct subtypes of inhibitory interneurons, parvalbumin (PV), somatostatin (SOM), and vasoactive intestinal peptide (VIP) expressing cells, have been identified as key players in flexibly modulating sensory responses [1]. The three interneuron populations have specialized local microcircuit motifs and are targeted differentially by neuromodulators and top-down inputs from higher-order cortical areas. However, the distinct contribution of each interneuron subtype to modulating a cortical network’s d