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Topic: spatiotemporal XOR task

ePoster
1 ePoster

In Neuroscience

ePoster · Neuroscience

Experimental and computational evidence of learned synaptic dynamics to enhance temporal processing

Jamie McDowell, Shanglin Zhou, Dean Buonomano · COSYNE 2025

One of the most fundamental tenets in neuroscience is that information is stored in the strength of synapses, and that learning relies on changes in synaptic strength. Here we aim to extend this tenet into the temporal domain by proposing that synapses not only learn to strengthen or weaken, but can learn when to be weak or strong on the subsecond scale. It has been known for more than half a century that synapses exhibit short-term synaptic plasticity (STP): a form of presynaptic, use-dependent, plasticity in which consecutive spikes can elicit progressively depressing (short-term depression/