Topic: Spike correlogram

Working memory (WM) maintains information during a delay period by internally generated neuronal activity. Here we report the dynamic organization of global cell-assembly activity that encodes WM information via cross-regional sequential spiking. Multiple Neuropixels-probe single-neuron recordings were made from over 60 brain regions in head-fixed mice performing an olfactory WM task. We found that neurons encoded WM during the delay period predominantly by transient activity that formed cross-region sequential waves, with the proportions of these neurons progressively reduced from olfactory t