Statistics of sub-threshold voltage dynamics in cortical networks
Oren Amsalem,Hidehiko Inagaki,Jianing Yu,Karel Svoboda,Ran Darshan · COSYNE 2022
Temporal irregularity and heterogeneities are key features of neuronal spiking activity in cortical networks. Simplified theoretical models of cortical circuits show that these features can be mechanistically accounted for if cortex operates in a fluctuation-driven regime (FDR). In FDR, excitatory and inhibitory currents are approximately balanced, and activity fluctuations emerge intrinsically from the non-linear network dynamics. However, it is still unclear if cortex operates in this regime. We address this question by analyzing sub-threshold membrane potential of neurons in sensory and fr
Fri, Mar 18, 2022