Automatized curation of spike sorting clusters
Anoushka Jain, Kleinjohann Alexander, Federico Spurio, Severin Graff, Björn Kampa, Jurgen Gall, Sonja Grün, Simon Musall · FENS Forum 2024
The availability of high-density electrophysiology techniques is transforming systems neuroscience, enabling experimental labs to record activity from hundreds of neurons throughout the brain simultaneously. However, extracting single-cell activity from the resulting large datasets remains challenging, as various experimental conditions introduce sources of contaminating noise, and even optimized spike-sorting algorithms may produce false positive units. This requires labor-intensive manual evaluation of spike clusters.To address this challenge, we extended existing analyses and incorporated m
ePoster · Neuroscience