Neuroectodermal stem cells contribute to the functional and morphological improvement of chronic spinal cord injuries via various mechanisms
Máté Ignácz, Tamás Bellák, Krisztián Pajer, László Gál, Zoltán Fekécs, Dénes Török, Annamária Marton, Csaba Vizler, Sudheer Babu Sangeetham, Antal Nógrádi · FENS Forum 2024
Spinal cord contusion injury leads to severe tissue loss and subsequent deficit of motor, sensory and vegetative functions below the lesion site. In this study we investigated whether transplantation of neuroectodermal stem cells into the injured rat spinal cord is able to induce significant morphological and functional improvement in a chronic spinal cord injury model. Mouse embryonic clonal neuroectodermal stem cells (NE-TR-4C) were grafted intraspinally five weeks after a spinal cord contusion injury performed in SD rats. Control animals underwent contusion injury without stem cell transpla
ePoster · Neuroscience