Understanding network dynamics of compact assemblies of neurons in zebrafish larvae optic tectum during spontaneous activation
Nicole Sanderson, Carina Curto, Enrique Hansen, Germán Sumbre · COSYNE 2023
How does intrinsic network structure shape spontaneous coordinated neural dynamics? Previous work has shown that overlapping tectal neuronal assemblies can be circuit mechanisms for robust visual detection [1]. To better understand how these assemblies give rise to emergent dynamics, we use single-photon calcium imaging of triple transgenic zebrafish larvae optic tectum (OT), letting us simultaneously record spontaneous activity of 1000s of neurons in the absence of stimulation. What is the composition of cell types within the assemblies? What role do the inhibitory and excitatory neurons play
Sat, Mar 11, 2023