Topic: spontaneous cortical activity

Early in development, spontaneous cortical activity in ferrets is organised into modular, low-dimensional patterns, and this organisation is highly similar across multiple cortical areas [1]. Currently, it is unclear how cortical activity changes in development, whether these changes reflect the different functional specialisations across cortical areas, and what circuit changes underlie these changes.Here, we investigated how the structure of spontaneous cortical activity changes over the course of development by recording it with two-photon calcium imaging before (P21-24), around (P27-32) an