Topic: spontaneous motor bouts

Rodents rely heavily on somatosensation to explore their environment. The primary somatosensory cortex (S1) contributes to the encoding and perception of tactile stimuli. Although S1 neurons also receive non-tactile inputs, it is unclear whether S1 similarly encodes non-tactile sensory-based behaviour. Whole-cell patch clamp recordings were used to investigate the voltage response of layer 2/3 (L2/3) pyramidal neurons in S1 during performance in either a tactile-based or auditory-based association task in mice. A robust and sustained voltage response was evoked in L2/3 pyramidal neurons during