Topic: state-conditioned decoding

Neurons' coordinated firing generates meso- and macro-scale network activity and oscillations. These, in turn, influence the individual neurons’ firing. An example of this cross-scale modulation is phase precession, where the phase of the theta oscillation, as measured by local field potentials (LFP), governs hippocampal place cell firing. By introducing a new method referred to as state-conditioned decoding, we uncover a different cross-scale hippocampal modulation. Unlike in phase precession, here the LFP’s spectral properties (i.e., instantaneous frequency and amplitude) modulate the firing