Exploring individual differences and stimulation parameters in amygdala-mediated memory modulation
We previously have demonstrated that brief electrical stimulation to the basolateral amygdala (BLA) reliably enhances declarative memory in humans after a one-day delay without eliciting an emotional response. In the current study 31 drug-resistant epilepsy patients undergoing stereo EEG surgery with depth electrode contacts implanted in various MLT regions. During continuous intracranial EEG recording, each participant was presented with a series of images of neutral objects. Across patients, we delivered a brief stimulation to the BLA (8 trains of 50-Hz pulses at 0.5 mA) before, during, or a