Label-free spectroscopic imaging of ex vivo Alzheimer’s disease brain from an animal model of tauopathy
Hao Meng, Mansfield Jessica, Michelle Bailey, Mark Frogley, Gianfelice Cinque, Moger Julian, Nick Stone, Francesco Tamagnini, Francesca Palombo · FENS Forum 2024
Alzheimer’s Disease (AD) is the main form of dementia, currently affecting more than 55 million people worldwide. There is a pressing clinical need for a definitive diagnostic test and effective therapy for AD. Light-based label-free techniques are particularly promising as they provide 3D imaging capabilities with chemical specificity and subcellular resolution. Vibrational spectroscopy methods have reached a level of advancement which enables translational medicine and potential for diagnosis and therapy. Our previous work has applied Fourier Transform Infrared (FTIR) imaging, Raman and Bril
ePoster · Neuroscience