Topic: stimulus-evoked spiking activity

Recent developments in experimental techniques have enabled simultaneous recordings from thousands of neurons, enabling the study of functional cell assemblies. However, determining the patterns of synaptic connectivity giving rise to assemblies remains challenging. To address this, we developed a complementary simulation-based approach, using a detailed, large-scale cortical network model. Using a combination of established methods we detected functional cell assemblies from the stimulus-evoked spiking activity of 185’000 neurons. Then, we studied how the structure of connectivity influences