Circulating microRNAs and isomiRs as biomarkers for the initial insult and epileptogenesis in four experimental epilepsy models – The EPITARGET study
Silvia Zucchini, Erwin A. van Vliet, Mirte Scheper, James D. Mills, Noora Puhakka, Kinga Szydlowska, Manuela Ferracin, Francesca Lovisari, Marie Soukupova, Prashant K. Srivastava, Michael R. Johnson, Katarzyna Lukasiuk, Jan A. Gorter, Eleonora Aronica, Asla Pitkanen, Michele Simonato · FENS Forum 2024
Epilepsy prevention is an urgent and global unmet need today. Particularly, in structural epilepsies that may occur months or even years after an epileptogenic insult (e.g., stroke, tumor, trauma, or status epilepticus), this latency time provides a window for preventive treatments for individuals at risk of developing epilepsy. In this regard, the identification of biomarkers to detect the subgroup of individuals with an increased risk of epilepsy after the epileptogenic insult is essential for the development of preventive treatments.A multicenter study was conducted using four different mod
ePoster · Neuroscience