Interactions between the subthalamic nucleus and the primary motor cortex control parkinsonian motor and nociceptive disorders
Elba Molpeceres, Rabia Bouali-Benazzouz, Juliette Viellard, Juliane Bonneau, Frédéric Naudet, Théo Lahitte, Pascal Fossat, Abdelhamid Benazzouz · FENS Forum 2024
The subthalamic nucleus (STN) holds a strategic position in the basal ganglia circuit, controlling both motor and non-motor functions. Alterations in its neuronal activity have been shown to be involved in the pathophysiology of Parkinson’s disease (PD). In addition to its classical intra-basal ganglia connections, STN neurons also project to several cortical areas. However, the degree of involvement of these subthalamo-cortical projections in motor and non-motor functions, and in the pathophysiology of PD has never been characterized.The aim of this study was to investigate the effects of inh
ePoster · Neuroscience