Antidepressant-like effect of curcumin in olfactory bulbectomized model of depression in male Wistar albino rats: Antidepressant behavior screening tests
Sandip Shah, Sarun Koirala, Laxman Khanal · FENS Forum 2024
The main objective of the study was to investigate the antidepressant like effect of curcumin in olfactory bulbectomized model of depression of male wistar albino rats through behavior screening tests. Bilateral olfactory bulbectomy was performed with rats anesthetized under ketamine (50 mg/kg/i.p.).Twenty male albino wistar rats, weighing 150–220 gm were randomly allocated into four groups (n=5)- Group A (control), Group B(olfactory bulbectomy;OB), Group C {vehicle (0.9% NS, 10 ml/kg) +olfactory bulbectomy,OB} & Group D {curcumin (40 mg/kg)+ olfactory bulbectomy;OB}.Behaviour screening te
ePoster · Neuroscience