All-Optical Investigation of Schaller Collateral Synapses in vivo
Cynthia Rais & J. Simon Wiegert · COSYNE 2023
Ensembles of neurons in the hippocampus encode the position of an animal navigating in the environment. Although exposed to the same environment over days, the neuronal representation is drifting and new ensembles emerge. Nonetheless the animal’s behavioral performance appears stable over time despite the neuronal drift. While the cellular dynamics of hippocampal coding are well-described, how information is encoded and preserved at the level of individual synapses during spatial navigation is less understood. The drift of the spatial representation in the hippocampus could be a consequence of
Sat, Mar 11, 2023