Topic: synaptic-cytoskeletal interactions

Understanding the intricate interplay between dendritic, cytoskeletal organization, and synaptic compartmentalization is crucial in deciphering neuronal function. While much is known about the role of actin filaments and microtubules in excitatory neurons, their organization in inhibitory GABAergic neurons remains relatively understudied. This research delves into the distinct cytoskeletal organization within aspiny GABAergic Parvalbumin-positive neurons, particularly focusing on their dendritic microtubule arrangement and its interaction with postsynaptic sites. Unlike excitatory neurons wher