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Topic: synaptic vesicle-associated phosphoprotein

ePoster
1 ePoster

In Neuroscience

Synapsin II differential modulation of presynaptic voltage-gated Ca2+ channels in excitatory synapses

Caterina Canevari, Matteo Moschetta, Emanuele Carminati, Antonella Marte, Pietro Baldelli, Fabio Benfenati · FENS Forum 2024

Synapsin II (Syn II), a pivotal member of the synapsin family, is a synaptic vesicle-associated phosphoprotein which plays critical roles in regulating neurotransmitter release at both excitatory and inhibitory synapses within the central nervous system. Synapsins contribute significantly to synaptic plasticity and maintain the delicate balance between excitatory and inhibitory synaptic transmission. Notably, mutations in synapsins genes have been identified in forms of epilepsy with or without ASD. Syn II has been shown to interact with the presynaptic calcium channel P/Q, but the functional

ePoster · Neuroscience