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Topic: synchronized bursting events

ePoster
1 ePoster

In Biology and Cell Biology

ePoster · Developmental Neuroscience

Local E/I Balance and Spontaneous Dynamics in Neuronal Networks

Shreya Agarwal, Richmond Crisostomo, Ulrich Egert, Samora Okujeni · Bernstein Conference 2024

The emergence of spontaneous activity in the form of synchronized bursting events (SBE) is considered to play a crucial role in activity-dependent development of neuronal networks. As inhibition matures, the spatiotemporal structure of activity becomes increasingly influenced by the balance between excitation and inhibition (E/I). Moreover, intricate interactions between excitatory (ENs) and inhibitory (INs) neurons may arise during their activity-dependent structural differentiation. However, how the resulting spatial embedding of INs and ENs in a network impacts on the spatiotemporal structu