Topic: taCasp3 AAV

Sleep and wakefulness are controlled by specific brain regions. These regions have been identified by classical elimination of brain regions or by acute manipulation of neural activity. However, acute manipulation of these regions often has only a temporary effect on the sleep-wake cycles and chronic inhibition of neural activity in these areas has little effect. These may have been an adaptation and compensation by other brain regions. The preoptic area (POA) has long been recognized as the sleep center first proposed by von Economo. However, a recent optogenetic study found that photostimula