Topic: tactile discrimination task

Sensory discrimination tasks are valuable tools for investigating neuronal perception and learning mechanisms. While novel somatosensory discrimination tasks have been developed for electrophysiological or imaging studies in head-fixed mice, there remains a scarcity of tasks incorporating neurophysiological recordings within a more ecologically realistic setting involving freely moving animals. This study introduces a tactile discrimination task for freely moving mice, integrating electrophysiology and calcium imaging with cellular resolution. In this go/no-go paradigm, mice learn to discrimin