Different somatosensory brain activity after high and low frequency rTMS in non-human primate model of central post-stroke pain
Kazuaki Nagasaka, Noriyuki Higo · FENS Forum 2024
Central post-stroke pain (CPSP) is a chronic pain resulting from cerebrovascular accidents in somatosensory pathways including thalamus, and clinical findings suggest that the mechanism involves abnormal brain activity and network reorganization due to maladaptive plasticity. Neuromodulation technique, such as repetitive transcranial magnetic stimulation (rTMS) targeting primary motor cortex (M1) have shown promise for the treatment of intractable pain, and high-frequency rTMS (Hf-rTMS) exhibits analgesic effects compared to low-frequency rTMS (Lf-rTMS), while its analgesic mechanism is unknow
ePoster · Neuroscience