Intrinsic excitability of anterior to posterior insula (aIC-pIC) projection neurons are differently modified following retrieval of aversive conditioning
Sailendrakumar Kolatt Chandran, Haneen Kayyal, Federica Cruciani, Adonis Yiannakas, Efrat Edry, Kobi Rosenblum · FENS Forum 2024
Identifying and avoiding potentially harmful food is crucial for the survival of many organisms. Conditioned taste aversion (CTA) is an associative learning paradigm when a novel appetitive tastant (e.g., saccharin) paired with a malaise-inducing agent, such as intraperitoneal injection of lithium chloride (LiCl), induces an aversion towards the same tastant when presented again. Recently, we have demonstrated that taste valence is encoded, at least in part, by changes in the intrinsic and synaptic properties of layer V/VI projecting neurons in aIC. Recent rodent studies have demonstrated that
ePoster · Neuroscience