Topic: temporal selectivity

In all sensory systems, arrays of receptors respond to stimuli over both space and time. Whether and how the precise temporal pattern of receptor activation impacts the activity of downstream brain regions remains unclear. In the olfactory system, odors activate stereotyped spatiotemporal sequences of olfactory bulb (OB) glomeruli, whose responses reflect the activity of olfactory receptor neurons. These glomeruli project via OB mitral and tufted (M/T) cells to downstream piriform cortex (PCx), forming a shallow circuit through which to assess how temporal patterns of receptor activity are enc