Topic: terpenes

Alzheimer's disease (AD) is the leading cause of dementia during aging. While its pathological hallmarks have been identified, disease-modifying treatments are not yet available. Therefore, there is increasing interest in studying lifestyle interventions that could help in the prevention and mitigation of the symptoms. In this context, we aim to study the effect of green exposure and particularly of phytochemicals inhalation, focusing on terpenes, specifically pinene, widespread in Italy. For this purpose, we set up two stem cell models of AD. The first is NE-4C, a murine neural stem cell line