Topic: Tet-On/Tet-Off system

Birds are excellent models to study learning, complex cognition, song and vision. However, to understand how these behaviors are realized within the brain, methods that are able to record and control cellular activity on a millisecond timescale are essential. Recent advancements in novel methods, such as optogenetics, calcium imaging or DREADDs, have revolutionized rodent research, but are not yet widely used in avian research. This is in part due to the fact that these methods rely on the introduction of genetic information for artificial ion channels or sensors. In the absence of transgenic