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Topic: threshold linear rate model

ePoster
1 ePoster

In Applied Mathematics and Biology

ePoster · Computational Neuroscience

Neocortical Modulation of Sharp Waves in a Rate Model of CA3

Atilla Kelemen, Stefano Masserini, Richard Kempter · Bernstein Conference 2024

Sharp wave-ripples (SPW-Rs) are widely studied oscillatory patterns observed during sleep and awake immobility in the hippocampal formation of most mammals [Buzsáki, 2015]. During SPW-Rs behavioral sequences are replayed compressed in time [Wilson & McNaughton, 1994; Diba & Buzsáki, 2007], which led to the hypothesis that they are mediating memory transfer from the hippocampus to the neocortex [Buzsáki, 1989]. SPW-Rs can be internally generated in the highly recurrent CA3 network [Maier et al., 2003], but their incidence during sleep is affected by slow oscillations in the cortex [Sirota et al