Neuronal biomarkers associated with recovery of motor function in a mouse model of stroke
Livia Vignozzi, Stefano Varani, Emanuela Beretta, Alessandro Leparulo, Stefano Vassanelli, Gabriele Deidda, Manuela Allegra · FENS Forum 2024
Ischemic stroke, a major cause of adult disability, results from the blockage of blood flow to the brains, leading to neurological impairments. After a stroke, the neural circuits in the peri-infarct zone undergo plastic changes to allow a spontaneous restoration of the neurological function. However, the extent of spontaneous recovery is highly variable among patients, underscoring the need for neurophysiological biomarkers to predict recovery outcomes and guide treatment strategies. Employing a well-established model of ischemic stroke in mice, the distal middle cerebral artery occlusion (dM
ePoster · Neuroscience