Sleep-wake variations of electrodermal activity in bipolar disorder
Clàudia Valenzuela Pascual, Diego Hidalgo Mazzei, Ariadna Mas, Roger Borràs, Gerard Anmella, Filippo Corponi, Bryan Li, Marc Valentí, Antoni Benabarre, Iria Grande, Meritxell Gonzalez, Isabella Pacchiattori, Anna Bastidas, Isabel Agasi, Marina Garriga, Eduard Vieta · FENS Forum 2024
The sympathetic system reacts to affective states, resulting in electrodermal activity (EDA) changes. According to prior research, EDA could be associated with Bipolar Disorder (BD) mood episodes, but results remain inconclusive due to heterogeneous study design and the presence of cofounders. During sleep main confounders such as physical activity and marked temperature changes decrease. Therefore, we measured EDA with wearable devices during the day and night to explore whether EDA is a better biomarker of mood episodes during sleep. We analysed 140 participants from the TIMEBASE study, 102
ePoster · Neuroscience