Protective effect of some natural antioxidants on olfactory ensheathing cells exposed to amyloid-β toxicity: A potential therapeutic role in preserving neurodegenerative diseases
Rosalia Maria Pellitteri, Maria Assunta Chiacchio, Michela Spatuzza, Giuseppina Raciti, Agata Campisi · FENS Forum 2024
In recent years, attention has grown on neuro-nutraceuticals and their effect on the health of the nervous system, since many compounds are characterized by antioxidant and anti-inflammatory activities. In the present study the effect of natural compounds (NCs), such as astaxanthin, curcumin and berberine was immunocytochemically assessed on expression of some cytoskeletal proteins, such as vimentin, Glial Fibrillary Acid Protein (GFAP) and nestin (a marker of precursor neural stem cells) in Olfactory Ensheathing Cells (OECs) exposed to amyloid-β (Aβ). In addition, we investigated on tissue tr
ePoster · Neuroscience