Homeostatic regulation of synaptic connectivity across connectomes
Andre Ferreira Castro, Ingo Fritz, Feiyu Wang, Ricardo Chirif Molina, Mikołaj Maurycy Miękus, Julijana Gjorgjieva · Bernstein Conference 2024
Body size varies across 21 orders of magnitudes in the animal kingdom [1]. In contrast to most organs, which scale through the proliferation of dividing cells of similar size, brains expand by modulating the size of non-dividing neuronal cells to innervate space during development [2]. Consequently, there is a notable variation in neuronal size and structure within individual brains and across species [3]. Considering that size inherently affects the rates of biological structures and processes, from cellular metabolism to information processing [4], the ability of neurons to maintain essentia