Topographically organized sensory-motor activity of dorsal raphe and its forebrain innervations modulate resting-state and sensory-evoked forebrain activity and animal behavior
Aytac Kadir Mutlu, Bram Serneels, Christoph Wiest, Anh-Tuan Trinh, Ricarda Bardenhewer, Oda Bjørnevik Håheim, Inger Kristine Fjeldskaar Aukrust, Fabrizio Palumbo, Emre Yaksi · FENS Forum 2024
The dorsal raphe nucleus (DRN) modulates diverse behaviors and brain functions through its extensive serotonergic projections across the forebrain. Recent studies showed that vertebrate DRN is composed of distinct types of molecularly defined and topographically organized populations of neurons that are evolutionarily conserved. However, how and what do these topographically organized DRN neuron ensembles communicate to the forebrain, and the role of DRN in forebrain computations and animal behavior remain elusive. Here, we employed two-photon calcium imaging in juvenile zebrafish to investiga
ePoster · Neuroscience