Unveiling the structure of the grid cell code in novel environments
Ben Sorscher, Surya Ganguli, John Wen, Lisa Giocomo · COSYNE 2023
Understanding how the brain builds maps of novel environments on behavioral timescales (seconds-minutes) is a fundamental question for neuroscience. Theoretical works posit a Hebbian plasticity mechanism for integrating novel landmarks [1]. Drosophila have been shown to use such a mechanism to integrate novel landmarks on timescales of minutes [2,3]. However, current evidence suggests that plasticity in the medial entorhinal cortex (MEC) operates on the timescale of days [4] — leaving open the question of how the mammalian brain maps novel environments on behavioral timescales. Here we investi
Sat, Mar 11, 2023