Topic: training context

Acquisition, consolidation, and retrieval of recent and remote memory rely on the coordinated neuronal activity of different brain regions. Inhibitory neurons, or Interneurons (IN), play a critical role in shaping neuronal networks by selectively gating signal flow. Parvalbumin-IN (PV-IN) is one of the predominant interneurons and is known to be involved in memory consolidation and development. However, its role in maintaining memory specificity is still elusive. Here, we perturbed PV-IN activity and found that the activity of PV-IN is needed to maintain recent memory specificity. Interestingl