Transcutaneous vagus nerve stimulation (tVNS) as a therapeutic approach towards the functional deterioration of the locus coeruleus–noradrenergic system
Kaushik More, Cristian González-Cabrera, Andres Jaramillo Flautero, Aleksandra Gritskova, Matthew Betts, Matthias Prigge · FENS Forum 2024
The Locus coeruleus (LC), the main noradrenaline-producing nucleus in the brain, is affected in a wide range of neurological conditions such as Parkinson's disease and Alzheimer's disease. Notably, the locus coeruleus-noradrenergic (LC-NA) system can be a therapeutic target through Vagus Nerve Stimulation. Transcutaneous auricular Vagus Nerve Stimulation (taVNS), an alternative technique that stimulates the auricular branch of the vagus nerve, is being studied as it’s less invasive, yet the nuanced neurocircuitry linking this branch of the vagus and LC remains unelucidated, as does the optimal
ePoster · Neuroscience