Topic: traumatic nerve injury

Chronic pain is a major disease burden with high incidence compared to other chronic diseases and with high persistence among affected individuals over many years.Satellite glial cells (SGCs) is a supportive cell type that ensheath the body of sensory neurons in the peripheral nervous system and in health SGCs are believed to contribute to neuronal homeostasis. However, evidence suggests that in certain disease states such as a traumatic nerve injury, satellite glial cells contribute to the development of chronic pain. Recent advances in single-cell RNA sequencing (scRNAseq) have prompted the