Training potentiates the efficacy of the adipose-stromal vascular fraction autograft on functional recovery after an acute spinal cord contusion in rats
Céline Ertlen, Maxime Bonnet, Mostafa Seblani, Thelma Coyle, Philippe Kachidian, Jean-Michel Brezun, Patrick Decherchi, Nicolas Serratrice, Tanguy Marqueste · FENS Forum 2024
Spinal cord injuries (SCI) are a major health concern, resulting in substantial functional deficits, including vegetative, motor and sensory impairments around and below the affected area. Despite continuous efforts, current spinal cord repair strategies have proven ineffective. The adipose-derived stromal vascular fraction (SVF) contains cells with trophic, pro-angiogenic, and immunomodulatory effects. Our previous study demonstrated that autologous SVF transplantation did not induce endogenous inflammation in SCI rats 14 days after injury. Additionally, it showed the benefits of autologous S