Histological, cellular, and molecular changes induced by chronic exposure to the (neuro)endocrine disruptor tributyltin in a widely used invertebrate model species
István Fodor, János Schmidt, Réka Svigruha, Zita László, László Molnár, Zsolt Pirger · FENS Forum 2024
Contamination by tributyltin (TBT) has historically been one of the major threats to aquatic environments due to its rapid bioaccumulation and high toxicity even at low concentrations. Recent studies reported that TBT could alter lipid metabolism, pointing out that more detailed studies are required to understand its multifaceted impact in aquatic animals.Adult (4-5-month) specimens of the great pond snail (Lymnaea stagnalis) were exposed to 100 ng/L TBT for 21 days. Potential histological, cellular, and molecular alterations were investigated in the CNS, kidney, and hepatopancreas.In the CNS,
ePoster · Neuroscience