Understanding neuromodulation pathways in tDCS: Brainstem recording following DC-TNS in anesthetized rats
Alireza Majdi, Amelien Vreven, Nelson K. Totah, Lars E. Larsen, Robrecht Raedt, Myles Mc Laughlin · FENS Forum 2024
The growing application of transcranial direct current stimulation (tDCS) in both experimental and clinical settings prompts an exploration of its underlying neurobiological mechanisms. Emerging evidence suggests that tDCS indirectly modulates brain activity via cranial nerve pathways, notably the trigeminal nerve. These pathways play a role in controlling neurotransmitter release and possible upstream effects. However, the electrophysiological effects of direct current stimulation on the trigeminal nerve (DC-TNS) within brainstem nuclei remain uncharted territory.Hereby, DC-TNS (± 0.25- ± 3 m
ePoster · Neuroscience